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Septic cardiomyopathy (SIC) In a model of LPS-mediated septic cardiomyopathy, some researchers revealed that LPS caused ferroptosis and septic cardiac injury by downregulating GPX4 protein levels and increasing COX-2 [93]

J Ethnopharmacol 2006

Finally, the cell nuclei were labeled with DAPI

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For example, acute mitochondrial dysfunction caused by FABP5 suppression upregulates IL-10 expression via the mtDNA-cGAS-STING pathway, enhancing the immunosuppressive potency of Tregs [112]

Vitamin D deficiency has even been called an ignored epidemic. More than a billion people across the globe have a vitamin D deficiency