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The positive effects of the diet are attributed to maintaining a state of nutritional ketosis, which is also a marker for compliance to the diet and assessed by elevated levels of ketone bodies such as acetoacetate in the urine, beta-hydroxybutyrate (BHB) in the blood, and acetone in the breath (7, 8)
Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion
Glucagon Like Peptide 1 (GLP-1) mimetic drugs which mimick the action of native GLP-1 as an incretin hormone have become a common second line of therapy for Type 2 diabetes (61, 80)
Given my history of [specific condition] and the difficulty I have had achieving sustained weight loss through lifestyle modification alone, this seems like an evidence-based treatment that could address the underlying biology." Notice the language
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