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Actually, this is a very active topic of research

Our findings indicate that GLP-1 secretion remains comparable between saline- and Donor+Cas9-treated DIO mice, suggesting that genome editing-mediated Exe4 secretion does not disrupt endogenous GLP-1 regulation (Supplementary Fig

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4.4 Pharmacological approaches Although many drugs have been reported to target TMAO production, but further studies and clinical trials are needed to confirm their safety and efficacy

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