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Funding: This study was supported financially by the National Science Council, Taiwan, under Grant No

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Utilizing fluorescein-labeled peptide, analysis of dual receptor agonists, exendin-4 and liraglutide, identified that agents with higher BBB permeability have improved protective effects, with DA5CH showing the highest efficacy [109, 110]

Most users tolerate this range without gastrointestinal upset, though doses above 5 grams may cause loose stools

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