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The finding of lower levels of H 2 O 2 in this study is in contrast to earlier reports where elevated levels of H 2 O 2 production were reported in immortalized renal proximal tubular epithelial cells from 4- to 8-week-old SHR, and renal cortical cells from 3-month but not 12-month-old SHR

Acta, Proteins Proteomics 130 PicaA.Russo KraussI.CastellanoI.RossiM.La CaraF.GrazianoG.et al (2012)

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Adherence during the baseline period was calculated as the proportion of days covered out of the 180 days prior to FSL acquisition

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During the course of the disease, motor neurons in the brain and the spinal cord degrade, causing progressive muscle loss and eventually respiratory failure