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Because of that, Ozempic, which was originally developed to treat diabetes, has started to get prescribed as an off-label medicine for weight loss
Although these treatments may be effective at treating the symptoms of depression by increasing the availability of monoamines at the receptor site, they may not be successfully treating the underlying cause of this debilitating condition
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In one randomized controlled trial that included 60 participants with a BMI of 35 or higher and type 2 diabetes for 5 years, 75% of those who underwent gastric bypass surgery and 95% of those who underwent a type of metabolic surgery known as biliopancreatic diversion were diabetes-free two years later, but no one treated with non-surgical interventions alone experienced diabetes remission (Mingrone 2012)