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Adipose tissue plays a role in oestrogen metabolism, and changes in body composition might temporarily influence the hypothalamic-pituitary-ovarian axis, though this remains speculative

However, like all medications, semaglutide is associated with a range of potential adverse effects that patients and healthcare professionals should be aware of

Cardiovascular risk is elevated in lupus patients, with studies showing an increased risk of coronary artery disease compared to the general population

Your healthcare provider may recommend baseline assessment of reflux symptoms and consider concurrent acid-suppressive therapy with proton pump inhibitors if needed

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