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They are distinguished by their capability to produce elevated levels of pro-inflammatory cytokines, including IL-1, IL-6 and TNF- [79]

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Injectable GLP-1 therapies have faced persistent challenges in real-world settings, including supply shortages, high monthly costs, and discontinuation rates linked to side effects and needle aversion

Practical Prescription Strategies The use of GLP-1 RA and SGLT-2 inhibitors has been proven to show cardiovascular risk reduction, unlike insulin use