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This differentiated status of DMSO-treated HepaRG cell cultures was routinely checked by their phase-contrast microscopy analysis, demonstrating the presence of hepatocyte-like islands and the formation of bile canaliculi, as previously reported ( 39 )

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J Dermatol Sci (2005) 37:613

Bicarbonate prevents degradation of the nutrient by neutralizing toxic by-products such as peroxide and free oxygen

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