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1-6 It causes inflammation in the musculoskeletal structures of the shoulder such as the bursae, tendons and ligaments, resulting in shoulder pain and a limited range of motion that can persist for months without treatment

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The human data, while limited, is directionally aligned with decades of preclinical work across multiple species

And evidence suggests stopping the drugs seems to reverse many of those health benefits as well

Functional genomics of OCTN2 variants informs protein-specific variant effect predictor for Carnitine Transporter Deficiency