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FDA has authorized extended expiration dates for these lots to reflect the 12-month product shelf-life (see Table 1 below), when stored according to the storage conditions detailed in the authorized Fact Sheet for Health Care Providers and the Letter of Authorization for Emergency Use Authorization (EUA) 105 for Paxlovid

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24 Large molecular size and structural complexity make biologics highly susceptible to degradation by gastric acid and digestive enzymes, leading to loss of activity before absorption can occur

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