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C-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

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Amoxicillin (Clamoxil) was from Beecham

Given that almost identical IC50 values for MTX were obtained by MTT and calcein AM at 48 and 96 hours, either one or the other method was used to access cell viability, depending on experimental and laboratory logistics