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In preclinical research settings, NNMT modulation is investigated for its downstream influence on NAD + -related biochemical pathways and cellular energy regulation

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This has potential to alleviate supply shortages currently plaguing the class, and may provide an opportunity for Lilly to bring a lower-cost option to market, though Lillys pricing strategy for orforglipron is unknown and likely to be dependent upon clinical results

L., & Bell, C

Bitton, A