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According to in vitro and in vivo research, caffeine increases SOD2 activity by preventing acetylation-induced deactivation

32 This anti-inflammatory effect is critical, as prolonged inflammation can cause tissue damage and further complicate the healing process

Further studies also need to find whether 5-amino-1MQs effects last after ceasing treatment

The best medication is the one you can actually afford to take consistently for as long as you need it

Kamenecka, M

Additionally, SASP includes proteases like MMPs, which, while degrading some ECM components, also remodel the matrix in ways that can facilitate fibrosis progression and release matrix-bound growth factors (like TGF-) [28]