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The central clinical idea: the liver depends on the methionine cycle and transsulfuration pathway to balance methylation, homocysteine disposal, glutathione production and sulfur metabolism

Realistic expectation: Trial data place the first measurable weight separation in this window, but the numbers were still early-stage

Both factors make the skin remodeling task harder

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Peptic ulcer disease represents a logical target indication, with animal models demonstrating accelerated ulcer healing and reduced ulcer formation with both systemic and local BPC-157 administration

& Beijnen, J