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[20] ROS can form as a result of drought, injury, herbicides and pesticides, ozone, plant metabolic activity, nutrient deficiencies, photoinhibition, temperature above and below ground, toxic metals, and UV or gamma rays

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It was therefore concluded that NiCl 2 induces p38 MAPK-dependent lytic cell death and stimulates markers of premature eryptosis, which may explain the changes in hematological parameters observed in poisoning victims [420]

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