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Nausea affects approximately 32% of patients, but this typically occurs early in treatment and resolves within weeks

During this time, the brain may take time to adjust to a new energy supply, which can temporarily affect focus and mental clarity

While many insurance plans cover GLP-1 agonists for type 2 diabetes, coverage is far less consistent when the primary indication is weight loss

This trial enrolled 1,961 individuals with BMI 30 or BMI 27 + 1 weight-related condition who did not have diabetes mellitus

Faster absorption means more semaglutide reaching GLP-1 receptors in a shorter time window, and those receptors in the brain and gut respond accordingly