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Acetyl-L-Carnitine in Neuropathic Pain: Experimental Data

Via screening 18 HDACs for the potential delactylase activity, Zhao and colleagues reported that HDAC1-3 and SIRT1-3 could cleave L-lactyllysine marks in vitro [95], especially for nuclear HDAC1-3 serving as the most robust delactylases, suggesting a critical role of HDAC1-3 for the removal of histone lactylation [95]

In the existing work, AA-injected group, SOD, GSH, and TAC values were declined, although MDA level was elevated

These issues were mild and did not warrant discontinuation of the fast

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