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Additionally, semaglutide has been shown to have a comparable risk profile to other GLP-1 RAs with respect to gastrointestinal adverse effects in the IBD population (106)
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The researchers found that the estimated mean change in hemoglobin A1c (HbA1c) after 40 weeks was 1.8, 1.5, and 0.1 percentage points for cagrilintide-semaglutide 2.4 mg each, 1.0 mg each, and placebo, respectively
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