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Measurement of ROS Production ARPE-19 Cells (5,000/well) were seeded in white opaque 96-well plates (Corning, Sigma-Aldrich) and incubated overnight

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Mechanism of Action of Vitamin B12 on Neurotransmitters Vitamin B12 plays several important roles in the nervous system and its deficiency can lead to neurological symptoms and may contribute to the development of neurodegenerative diseases

At higher concentrations, it reduces MMP activity to prevent excessive collagen breakdown

Regulated Sleep Patterns Experience a more restful sleep as B12 plays a crucial role in regulating melatonin production, the hormone responsible for a good nights sleep