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The SURMOUNT-1 trial demonstrated significant weight loss, with patients losing approximately 15-21% of their body weight at the 15 mg dose over 72 weeks, depending on the statistical method used
It is being actively studied in models of obesity, type 2 diabetes, and metabolic syndrome for its ability to induce significant reductions in body weight and improve glucose control
The injectable Wegovy helps people lose an average of 15% to 16% of their body weight
Obes Res Clin Pract 17(5):411420 Thai K, Taylor MW, Fernandes T, Akinade EA, Campbell SL (2023) Topiramate alters the gut microbiome to aid in its anti-seizure effect
Semaglutide reduces your appetite but its eating less and healthier, and exercising regularly that causes weight loss, rather than the medication itself