Combination therapy with Sem and rosiglitazone was studied for diabetic retinopathy in rodent animals by decreasing the GFAP expression and inhibiting oxidative stress (Yang et al
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According to Dr Ambrish Mithal, chairman and head of endocrinology and diabetes at Max Super Speciality Hospital, Wegovy primarily targets GLP-1 receptors, while Mounjaro acts on both GLP-1 and GIP receptors, offering dual action
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The trials were conducted in accordance with the Declaration of Helsinki and its later amendments and the International Conference on Harmonisation Good Clinical Practice