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PMID: 21148341 [3] Sikiric P, et al

Biofactors 45, 152168

In vitro tools for biorelevant investigations are therefore highly desirable

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

doi:10.1007/s11655-022-3678-5 11

Although laboratory alterations are seen, such as a reduction in serum T 4 by 25%, T 3 by 15% and a 2 mU/L rise in TSH, these values remain within the normal ranges without clinical signs of thyroid dysfunction ( A failure of the Wolff-Chaikoff effect can give rise to the Jod-Basedow phenomenon, typically seen in patients with impaired thyroid regulation, including those with thyroid nodules