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Weight loss itself improves kidney function by reducing the metabolic burden on the kidneys, lowering blood pressure, and improving insulin sensitivity
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It has been shown that the stimulatory effect of GLP-1 on insulin secretion is, to some extent, dependent on PKC, as evidenced by the ability of the PKC activator phorbol 12-myristate 13-acetate to mimic the effects of GLP-1 on electrical activity
doi: 10.1159/000369863 [DOI] [PubMed] [Google Scholar] 32.Khateeb J, Fuchs E, Khamaisi M
M., & Azzi, A
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