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This explains why vomiting is more common during dose escalation and why gradual titration protocols are recommended in clinical practice

As of early 2026, the FDA has updated prescribing information for both Wegovy and Mounjaro

Despite recommendations to include the combination in patients with T2DM, cardiologists view diabetes care independently of cardiovascular care, and consequently, are reluctant to prescribe SGLT2is + GLP-1RAs for their cardiovascular benefits in the management of patients with T2DM [75, 76]

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and parties to a merger, financing, acquisition, reorganization, bankruptcy, or sale of business assets