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Clinical trial data indicate that GLP-1 RAs can achieve approximately 1520% weight reduction, but high cost often places ICERs above conventional willingness-to-pay benchmarks

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However, this was achieved using intraperitoneal injections with alum adjuvant, which likely contributed to the observed immunogenicity [56]

[4] [5] Some patients report dizziness during the initial 3 mg phase, with symptoms sometimes recurring temporarily when the dose is escalated

Insights into the roles of Apolipoprotein E in adipocyte biology and obesity