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Colloid Interface Sci

Since the discovery of FSP1, more and more GPX4-independent ferroptosis pathways have been discovered in various physiological and pathological processes Drugs targeting GPX4-independent ferroptosis pathway may become a new direction for the treatment of diseases

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Downregulation of CRAT promoted mitochondrial metabolism by increasing mitochondrial biogenesis in OC cells Considering that CRAT is an mitochondrial-localized enzyme catalyzing the conversion between acetyl-CoA and acetylcarnitine by adding and the removing carnitine from acetyl-CoA, we therefore assessed the role of CRAT in the regulation of mitochondrial metabolism by evaluating oxygen consumption rate (OCR), extracellular acidification rate (ECAR), OXPHOS complex activity, ATP and ROS productions

An insulin syringe is used and the needle is tiny (most people feel that it doesnt hurt at all once you know what you are doing!)