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Since it slows down digestion, people may experience nausea, stomach pain, bloating, gas, and other gastrointestinal-related issues after eating large portions or foods that take a long time to digest

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This approach helps your body adjust and minimizes gastrointestinal side effects

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While tirzepatide does increase metabolism through its own mechanisms, dramatic or unexpected weight loss should prompt a thyroid function check

Patients with renal impairment can generally use semaglutide and tirzepatide without dose adjustment, though monitoring for dehydration from gastrointestinal side effects is important