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Clin Biochem 2006

The main drug classes classically implicated in SS can be divided into serotonin precursors, inhibitors of serotonin reuptake from the synaptic cleft, inhibitors of serotonin metabolism, direct serotonin receptor agonists, and drugs that sensitise serotonin receptors (Table 1)

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One milestone was the development of nanostructured lipid carriers (NLCs) in the early 2000s as a second-generation lipid nanocarrier