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Analysis of our RNA sequencing data revealed a trend toward increased expression of key antioxidant genes, including GSTA14 and TXNRD1, after metformin treatment (Supplementary Fig

The involvement of DNA-damage and -Repair defects in neurological dysfunction

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Laboratory studies using animal models have explored mechanisms including angiogenesis (new blood vessel formation), modulation of inflammatory pathways, and cellular processes in tendons, ligaments, muscles, and connective tissues

range) 1-month IGF-I SDS was +1.4 (1.0