The trade-offs among clinical effectiveness, tolerability, and cost for GLP-1RA use have highlighted the importance of a cost-effectiveness analysis (CEA) of GLP-1RA versus insulin therapy in real-world clinical practice [2]
The Future: Multi-Agonist Era Tirzepatide Dual agonist: GLP-1 + GIP Produces: Exceptional HbA1c reduction Major weight loss Retatrutide Triple agonist: GLP-1 + GIP + Glucagon receptor Early trials demonstrated unprecedented weight loss results approaching bariatric surgery outcomes
They deliver rapid results but can inflate the cost of coverage even quicker
As a result, lipid peroxides accumulate in the cells ultimately leading to ferroptotic cell death [3-5]
Fortunately GLP-1s are easier than ever to obtain online, but with so many options in the telehealth space, it is imperative that you choose the right clinic
Store in a cool, dry place and keep out of reach of children