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All subjects were enrolled in a standard wound care protocol, where only the subjects with sharp ulcer wound or debridement were entered into this randomized, placebo controlled clinical trial

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Chronic oxidative stress and inflammation contribute to the failure of antioxidant defenses in diabetic patients, highlighting the importance of balancing ROS and antioxidants as a therapeutic strategy [26]

Several recent in vitro and animal studies have shown that ferroptosis inducers, chemotherapy, and immunotherapy can synergistically affect ovarian cancer [35,41]

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