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A well-known risk factor in humans is hypercholesterolemia, i.e., elevated total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) (Pourrajab et al., 2021), and other important contributors to this disease include inflammation, oxidative stress and insulin resistance (Subramani et al., 2017)

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Without adequate GSH, low NADPH results in increased reactive oxygen species (ROS)

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Archived from the original (PDF) on 17 October 2016