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Clinical Evidence 2026 Update: Phase 3 TRIUMPH Data In December 2025, Eli Lilly reported the first successful Phase 3 readout for retatrutide (LY3437943) from the TRIUMPH-4 trial

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(11) P Dick, C Costa, K Fayolle, M E Grandjean, A Khoshbeen, and R Tissot (1984) DSIP in the treatment of withdrawal syndromes from alcohol and opiates European Neurology, 1984, Volume 23 (Issue 5), Pages 364-71

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Therefore, disrupting the redox homeostasis of cancer cells by inhibiting glutamine metabolism may be an effective strategy for cancer treatment (Dewaele et al., 2010