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Journal of Neuroscience Research, 91(10), 1296-1305

BMC Med 13:225 Kanter J, Walters MC, Krishnamurti L, Mapara MY, Kwiatkowski JL, Rifkin-Zenenberg S, Aygun B, Kasow KA, Pierciey FJ, Bonner M (2022) Biologic and clinical efficacy of lentiglobin for sickle cell disease

TRPA1 channels promote astrocytic Ca 2+ hyperactivity and synaptic dysfunction mediated by oligomeric forms of amyloid- peptide

Also, it enhances neuronal resilience by reducing apoptosis, stabilizing calcium homeostasis, and preserving mitochondrial integrity while benefiting synaptic function through Ca 2+ -mediated signaling and cholinergic boosting

and Brown, L.M

Yang Q, Zhou J (2019) Neuroinflammation in the central nervous system: symphony of glial cells