ProHealth's cited clinical study (Dosz E et al., Nutraceuticals, 2025) reported a 26.4% improvement in digestive comfort associated with ButyroGen at the ingredient level
Another study showed that the addition of antibodies against IPG-P blocked the stimulatory effects of both IGF-1 on progesterone synthesis by swine ovary granulosa cells [118]
Plasma adiponectin levels in women with polycystic ovary syndrome: impact of metformin treatment in a case-control study
If you have sensitivities or allergies, we recommend doing a patch test before full application
in clinical trials both led to about a 15% reduction in body weight in 16 months
While direct SIRT3 activators are not yet clinically available, recent studies supported that SIRT3 activators reduced chronic inflammation and improved IR, such as berberine [36], honokiol [56] and guttiferone J [57]