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While these findings suggest potent fungicidal activity, the study represents a preclinical investigation, and further validation in larger, clinically relevant models are required to establish therapeutic relevance

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The ratio of Firmicutes to Bacteroidetes is a commonly-studied change with an increase often linked to HFD consumption/obesity in mice 43,44 and humans 45,46 (for review, see John and Mullin, 2016 47 )

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