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Thus, the -glutamyl cycle, apart from explaining the synthesis and degradation of glutathione, may serve as a generator of signals to activate amino acid transport into cells (75)

It is postulated that DM-induced oxidative damage may be more significant in erythrocytes than in other cells, due to their high content of iron and polyunsaturated fatty acids, as well as their role as oxygen transporters, with a high degree of exposure to free radicals [320]

J Inherit Metab Dis 35(3):541548

Mercury is known to adversely affect multiple organ systems, including the nervous, cardiovascular, and immune systems

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