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[51] : 694 Anatomically the median and lateral lobes are usually enlarged, due to their highly glandular composition

Researchers consulting recent reviews should attend to both the foundational mechanism papers cited in the references and the contemporary expansion-era publications that document ongoing methodological refinements and emerging research applications

While historically listed with an "unknown status," recent data releases in late 2025 and early 2026 have clarified the safety profile that helped justify the Category 1 reclassification. Study Design: A randomized, placebo-controlled, double-blind Phase 1 pilot study

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