Heilborn JD, Frohm Nilsson M, Chamorro Jimenez CI, Sandstedt B, Borregaard N, Tham E, Srensen OE, Weber G, Sthle M: Antimicrobial protein hCAP18/LL-37 is highly expressed in breast cancer and is a putative growth factor for epithelial cells
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The peptide is stable with a moderate half-life allowing once-daily dosing
Despite scholars repeatedly clarifying that there is no direct correlation between infrastructure and its structuring effects (Plassard, 1990), political decisions have nevertheless defined strategic development projects through an infrastructure-based approach (Offner, 1993
"While we acknowledge your response that an abrupt shortening of the enrollment period led to challenges and mistakes, your response is inadequate because, regardless of the length of the enrollment period, you are still responsible for ensuring that subjects meet protocol-specified eligibility criteria before you enroll them into the study," said FDA
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