can tirzepatide give you diarrhea Diarrhea: Clinical Facts & Genetic Context – PlexusDx Why Does Tirzepatide Cause Diarrhea​?

Around 3.1 to 3.8% of patients discontinued the treatment due to gastrointestinal side effects

The p53 pathway genes, namely, BAX, p21, MDM2, and TP5313, which are involved in DNA repair, apoptosis, and cell cycles were also up-regulated with EGCG treatment (Zhang et al., 2010a)

Importantly, while semaglutide delays gastric emptying, this effect has not been shown to have clinically relevant impacts on the absorption of most oral medications, as noted in the Wegovy SmPC

The element is stored in the body mainly in the kidneys, spleen and testes, as well as in soft tissues, bones and blood, where it can bind to proteins, mainly transferrin.

The weight benefit is also complementary

But Wegovy is formulated with a different ingredient, Semaglutide