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1,2 This review evaluates the proposed mechanisms of action of GLP-1RAs, critically analyses recent evidence from clinical trials and considers the optimal clinical use of GLP-1RAs and potential future directions

Average weight loss is usually 1525% of someones total body weight 3 after about one year (compared with about 23% when taking a placebo)

By promoting feelings of fullness, slowing gastric emptying, and reducing appetite, it supports weight loss for individuals who are overweight or obese

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