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Reactive gliosis and the multicellular response to CNS damage and disease

Pro-inflammatory chemicals called cytokines (IL-6, TNF-) and prostaglandins contribute to fibroid growth and the heavy bleeding associated with them. Women with higher dietary inflammatory index scores show greater fibroid risk in observational data. Insulin and Insulin-Like Growth Factor Insulin resistance and hyperinsulinemia stimulate IGF-1, which acts on fibroid tissue growth receptors

Miyagi Y, Om AS, Chee KM, Bennink MR (2000) Inhibition of azoxymethane-induced colon cancer by orange juice