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If approved, oral semaglutide could become the first oral GLP-1 therapy available for children and adolescents

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GLP-1R-targeted nanoplatforms are particularly well-suited to such customization due to their modular design and the availability of organ-specific targeting ligands

arXiv preprint arXiv:1909.11942

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Of interest, the basal metabolic rate, the minimum energy required to maintain vital body functions [93], in infants with PWS is slower than an infant without PWS, suggesting that infants with PWS require fewer calories than the healthy counterparts