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That being said, its crucial to understand that weight loss is a gradual process with semaglutide

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Despite these challenges, participants on semaglutide 2.4 mg achieved an average weight loss of 9.64%, with significant improvements in glycemic control

Key highlights Although semaglutide is an effective medication, some patients consider its alternatives due to cost and insurance issues, persistent shortages, intolerable side effects, insufficient results, certain health conditions, or a preference for pills

In eye diseases like DR, high blood glucose and oxidative stress activate the Notch1-Hes signaling pathway, leading to ECM imbalance and promoting vascular dysfunction, inflammation, and retinal damage (Fan et al., 2020)