doi: 10.3233/JPD-191900 15
Free Radic Biol Med 123:116124 Garg N, Joshi R, Medhi B (2020) A novel approach of targeting refractory epilepsy: need of an hour
Further, a key glutathione-synthesizing enzyme, glutathione cysteine ligase modifier (GCLM), is decreased under oxidative stress.95 GCL dysregulation and deficit glutathione inhibit the detoxification of oxidative stress that results from dopamine metabolism and consequently lead to neural injury, especially in dopamine neuron-rich regions.9697 Glutathione is reduced in the prefrontal cortex and striatum,949899100 which are closely associated with the psychopathology of schizophrenia
The clinical decision is straightforward
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Figure 3 Taken together, these data indicate that liraglutide treatment significantly improves hepatic steatosis and liver fibrosis in female SKO mice