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GLP-1 agonists like Semaglutide and Tirzepatide are currently the most potent peptides for fat loss

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Additionally, genes affecting appetite regulation (like MC4R rs17782313) and fat metabolism (FTO rs9939609) modulate how your body processes weight loss signals

Strategies to improve adherence include clear communication, addressing motivation and self-efficacy, and fostering social interactions while balancing exercise load and physical fatigue (Dionigi, 2007