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This controlled delivery explains why GHK-Cu restores copper-dependent enzymatic functions without metallic toxicity (Pickart & Margolina 2018 Int J Mol Sci)

It was first found in the brains of rabbits during research on sleep deprivation and later identified for its possible function in regulating the sleep-wake cycle in animals and humans

Description of the included studies Table 1 provides details and results of the 11 studies reviewed

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11 Pharmacological agents include HMG-CoA reductase inhibitors (statins) and fibric acids