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Since there is not enough intrinsic factor for vitamin B12 to bind with and it cannot travel to the distal ileum to absorb into the blood, the body cannot absorb vitamin B12 properly

AVEREL: A randomized phase III trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer

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These occurred without causing harm to other organs [4,10]

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In fact, injections and infusions may be more beneficial for people deficient in B12 due to a digestive issue or because they are older and have less stomach acid