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Subcutaneous injection distributes the peptide systemically, meaning it can affect skin throughout the body rather than only where directly applied

Practical tips for optimising B12 status include consuming B12-rich foods regularly throughout the week rather than sporadically, considering fortified foods if reducing animal product intake, and discussing supplementation with your GP or registered dietitian if you have absorption concerns

Targets collagen synthesis, tissue regeneration, skin repair, and anti-inflammatory pathways

61 Clinical trials in humans have evaluated the benefits of B12 in a number of painful conditions

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NEJM 2023: 10.1056/NEJMoa2301972 Phase 2 dose-response (1, 4, 8, 12 mg arms, 48 wk, non-diabetic obesity)